About

Iran with more than 8000 of plant species and other marine resources and also a rich source of traditional medicine, with different climate, would deserve to have a modern facility of natural product drug discovery with the acceptable tools and research approach in international scientific associations. The Biodiscovery Research Core try to collect these resources from different area of country and banking them in standard condition. This bank will be used for drug discovery with using of zebrafish bioassay system.

Member

  • Professor:

Dr. Yaser Tahamtani (Ph.D., Assistant Professor, Stem Cell Biology Royan Institute)

  • Collaborated Professor:

Hossein Ghadamyari (Ph.D., Assistant Professor, Clinical Biochemistry, Kerman University)

  • Senior Researcher:

Mohammad Rezaei (Ph.D., Researcher, Stem Cell Biology Royan Institute )

 

  • Researcher:

Dina Eghbal (M.Sc Student, Cell & Molecular Biology, University of Science & Culturere)

Sedighe Jalali (M.Sc Student, Molecular Biology, Guilan University)

Mahsa Moayedi (M.Sc Student, Molecular Biology, Kharazmi University)

Mohadese Hadian (M.Sc Student , Cell & Molecular Biology, University of Science & Culturere)

Sogol Kianersi (M.Sc , Researcher, Biomedical Engineering, Amir Kabir University)

Tayebe Hadi (M.Sc Student, Microbiology,  Alzahra University of Science & Culturere)

Parisa Fooladi (M.Sc, Researcher, Cell Biology, University of Science & Culturere)

Narges Shahbazi (Ph.D. Student, University Innsbruck)

Project

  • Generation of Transgenic Gcga: Tomato zebrafish model to detect α to β Cell Transdifferentiation.
  • Evaluation of 3 algae species treatment on beta cell regeneration by Tg(ins:kaede-NTR) transgenic zebrafish model.
  • Evaluation of different Eryngium species products activity in beta cell regeneration using Tg(ins:Kaede-NTR) zebrafish model.
  • Evaluation of type2 diabetes neuropathy in zebrafish.
  • Generation of transgenic zebrafish Tg(pdx1:RFP) as model to study pancreatic beta cell regeneration.

Publication

  • Salehpour, A., Rezaei, M., Khoradmehr, A., Tahamtani, Y., Tamadon, A. (2021) Which Hyperglycemic Model of Zebrafish (Danio rerio) Suites My Type 2 Diabetes Mellitus Research? A Scoring System for Available Methods. Frontiers in cell and developmental biology.

https://pubmed.ncbi.nlm.nih.gov/33791308/

  • Pourghadamyari, H., Rezaei, M., Ipakchi-Azimi, A., Eisa-Beygi, S., Basiri, M., Tahamtani, Y., Baharvand, H. (2019) Establishing a new animal model for muscle regeneration studies. Molecular biology research communications. 8:171-179

https://pubmed.ncbi.nlm.nih.gov/32042835/

  • Rezaei, M., Basiri, M., Hasani, S.N., Asgari, B., Kashiri, H., Shabani, A., Baharvand, H. (2019) Establishment of a Transgenic Zebrafish Expressing GFP in the Skeletal Muscle as an Ornamental Fish. Galen Medical Journal. 8

https://www.gmj.ir/index.php/gmj/article/view/1068

                                                                                                 

Facility

Open Position

  • Ph.D. student for generation of zebrafish immunology models.
  • M.Sc. student for drug screening in transgenic zebrafish.

Miscellaneous

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